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direct-to-implant

A cross-section from the implant outwards to the skin. Closest to the implant, the compact layer of the membrane, described by the manufacturer as providing a smooth surface towards the device. Above it, the porous layer, described as the side that supports early tissue integration, with small arrows showing cells and vessels entering it from the flap. Above that, the mastectomy flap and skin. A note reminds the reader to confirm orientation in the Instructions for Use for each configuration.
Clinical Insights — 12 October 2026

ExaShape in Practice: Which Configuration, Which Patient, and How to Use It

Why ExaShape, in which cases, which configuration, and how it is used in theatre, from the flap decision to the refinement stage.

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A two-axis diagram. The horizontal axis is additional benefit, the vertical axis additional cost, with the comparator at the centre. The top-right quadrant is more costly and more effective, where the question is whether the extra benefit is worth the extra cost. The bottom-right is cheaper and better, dominant. The top-left is costlier and worse, dominated. Three comparisons are placed schematically. DIEP flap against implant, top right, about 11,941 US dollars per breast-related QALY, judged cost-effective. Dermal matrix in two-stage expander reconstruction against none, just above the origin to the right, judged cost-effective. Dermal matrix against an autologous dermal flap in single-stage reconstruction, slightly above the origin with almost no extra benefit, 261,720 dollars per QALY, judged not cost-effective.
Clinical Insights — 09 October 2026

The Cost-Effectiveness of Breast Reconstruction: What Actually Drives the Numbers

Unit price is the least informative number in reconstruction economics. Complications, theatre time and the number of operations drive cost; the unit…

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Two timelines running left to right. Direct-to-implant: mastectomy and definitive implant in one operation, then healing, then optional refinement such as fat grafting. Two-stage: mastectomy with a tissue expander, then a series of expansion visits over several weeks to months, then a second operation to exchange the expander for the definitive implant, then optional refinement. A note states that the first operation decides which line the patient is on, and that the decision rests on the mastectomy flap.
Clinical Insights — 24 September 2026

Direct-to-Implant or Two-Stage: Reading a Meta-Analysis, a Trial and a Cohort Together

A meta-analysis, a randomised trial and a prospective cohort give three different answers. Selection on the mastectomy flap explains all three.

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The same implant drawn in two planes. Subpectoral, it sits under the pectoralis major, which has been divided along its lower border: the muscle gives extra soft-tissue cover over the upper pole, but it now contracts across the device, which is the mechanism of animation deformity and of post-operative pain. Prepectoral, the implant sits on the muscle, wrapped in a matrix and covered by the mastectomy flap alone: the muscle is left whole and undisturbed, so there is no animation and less early pain, and in exchange every demand shifts onto the quality of the flap and the soft-tissue cover above it.
Clinical Insights — 10 September 2026

Prepectoral or Subpectoral: What Changes When the Plane Changes

Prepectoral placement moves the burden from the muscle to the mastectomy flap. An improvement where the flap can carry it, a mistake…

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A mastectomy flap in cross-section with the four things assessed before committing to a one-stage reconstruction marked on it: thickness of the retained subcutaneous layer, the colour and capillary refill of the skin, dermal bleeding at the cut edge, and perfusion of the flap as a whole shown as a gradient that falls towards the distal tip and towards the areola. A panel beside it notes that the flap is judged after the mastectomy is finished and under normal blood pressure and temperature, because a cold, hypotensive patient makes a healthy flap look dead and warming and resuscitation change the reading.
Clinical Insights — 07 September 2026

Reading the Mastectomy Flap: The Decision That Is Still Open in Theatre

Direct-to-implant is a single-stage operation resting on a judgement made mid-operation. What is assessed, why it cannot be decided beforehand, and what…

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dti-cover-01
Clinical Insights — 03 August 2026

Direct-to-Implant Breast Reconstruction: Patient Selection, Technique and Evidence

A professional overview of DTI reconstruction: the selection criteria, the cautions, and where soft-tissue matrix support fits.

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