Regulatory &
Quality Standards

Advanced Biomedical Concept operates under a certified Quality Management System. All products are developed, manufactured, and released under strict compliance with EU Medical Device Regulation (MDR 2017/745) and carry the CE mark under the supervision of a Notified Body.

Our biological matrices are manufactured under GMP conditions from carefully selected, traceable bovine pericardium. Every production batch undergoes full biocompatibility, sterility, and mechanical performance testing before release.

EU MDR 2017/745

All ABC products are CE-marked under EU Medical Device Regulation 2017/745. Our technical documentation, clinical evaluations, and post-market surveillance plans are maintained in full compliance.

ISO 13485:2016

Our Quality Management System is certified to ISO 13485:2016 — the international standard for medical device quality management. Annual audits are conducted by our Notified Body.

ISO 10993 — Biocompatibility

Biological safety testing according to ISO 10993 is performed on all materials. Our pericardium-derived matrices undergo cytotoxicity, sensitisation, and implantation studies.

GMP Manufacturing

Production takes place in GMP-certified facilities in Italy. Full traceability from raw material selection through to finished device is maintained via our ERP system.

Clinical Evidence

Backed by Science & Data

7+
CE-marked products

Across breast reconstruction, augmentation, and fat grafting

100%
Biological origin

Sourced from carefully selected, traceable bovine pericardium

2+
Peer-reviewed papers

Published clinical data supporting product safety and efficacy

23+
Countries

International regulatory approvals and distribution network

Post-Market Surveillance

ABC operates a comprehensive PMS programme in accordance with MDR requirements. We systematically collect and analyse data from clinical use, literature, and vigilance sources to ensure ongoing safety and performance of our devices.

Vigilance Reporting

All serious incidents and field safety corrective actions are reported to competent authorities in accordance with MDR Article 87 timelines.

PMCF Studies

Post-Market Clinical Follow-up studies are conducted in partnership with clinical centres to generate long-term performance and safety data.

Complaint Handling

Our Quality team investigates all product complaints. Response targets: acknowledgement within 3 business days, resolution within 30 days for non-critical, 10 days for critical reports.

Downloads

Regulatory Documents

Download our quality and regulatory documentation. For IFU documents specific to each product, please visit the individual product pages.

Declaration of Conformity — Exashape® Range
PDF — Available on request
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ISO 13485:2016 Certificate
PDF — Available on request
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Post-Market Surveillance Summary
PDF — Available on request
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Instructions for Use (IFU) — All Products
See individual product pages
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Regulatory Enquiries

For regulatory affairs, technical documentation requests, or notified body correspondence, please contact our Quality & Regulatory team directly.

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