Exafat by Advanced Biomedical Concept
Fat Dialysing System

EXAllence in breast fat grafting

EXAFAT is an advanced fat grafting system for breast reconstruction, engineered specifically for breast surgery with closed-loop fat dialysis.

ReconstructionAugmentationExplantationReshaping
Complete System Includes
01
Harvesting Cannula
250 mm × 3 mm Ø — 12-port tri-lateral
02
Vacuum Locking Syringes ×2
20 mL — automatic 300 mmHg negative pressure
03
Fat Dialysing Station
Closed-loop — up to 200 mL/cycle
04
Injection Cannulas ×2
Spatulated & round tip — 150 mm × 2.1 mm Ø
05
Subcision Needle
Ultra-Sharp — 150 mm × 16 G
+ Needle 90 mm × 16 G · FLL–FLL Connector
ALL-IN-ONe

All you need in one sterile, ready-to-use kit

ALL-IN-ONE
One sterile, ready-to-use kit for the complete procedure
PURIFIED FAT
By Dialysis: active, gentle, continuous fat washing and filtration
VERSATILE
Subtle contouring to large-volume grafting procedures
THE STANDARD
Same tools every case — reproducible process, consistent techniques
USER-FRIENDLY
Intuitive and fast, saving OR time
THE WORKFLOW

Every component is engineered to streamline Breast fat grafting

Better Tools Refine Techniques
Better Techniques Improve Outcomes

Efficient fat harvesting
Dedicated cannula and automatic vacuum locking syringes for controlled and fast fat harvesting.
Gentle fat purification
Fat Dialysis Station — continuous washing and filtration, removing blood, oil, tumescent drugs, DAMPs and excess fluid.
Precise fat injection
Two blunt-tip cannulas: round tip for regular tissue and spatulated tip for scar tissue.
Optimal tissue expansion
16G subcision needle for precise scar release, fasciotomy and infusion.
The Core Technology

FAT DIALYSIS

REDEFINING PURIFICATION
BRIEF ACTIVE GENTLE CONTINUOUS
Fat Dialysis

Fat dialysis is a brief and active purification process that removes, in a continuous and gentle way, tumescent fluid, blood, drugs, oil and excess fluid from harvested fat.

EXAFAT employs a microfiltration technology with 50-micron pores, allowing liquid waste to pass through under controlled hydrostatic pressure while the purified fat — including the SVF niche — is retained.

The Result

Significant reduction of toxic and inflammatory triggers while maintaining the structural integrity and biological viability of the dialyzed adipose tissue.

Read the full guide to fat dialysis for breast fat grafting →

COMPARATIVE PERFORMANCE
EXAFAT vs DECANTATION & CENTRIFUGATION
OIL
FAT
FLUID
1EXAFAT retains 20% (±5%) of clean fluid, compared to 33% (±6%) of non-purified fluid with traditional decantation*.
2EXAFAT yields 18% avg. more purified fat than the same input volume processed by decantation*.
3EXAFAT yields 5% avg. more purified fat than the same input volume processed by Coleman centrifugation*.

Although both dialysis and centrifugation effectively concentrate fat, the dialysis method preserves a higher level of residual hydration without compromising the purified fat volume yield. This feature may positively impact graft take because:

1) It helps protect adipocytes and stromal cells from mechanical damage during injection

2) It enhances injectability and promotes a more uniform fat distribution within the recipient site

Current literature supports the idea that maintaining a certain degree of hydration — though not precisely defined — can help preserve cellular components and facilitate injection. In contrast, excessive dehydration has been associated with increased shear stress and reduced adipocyte viability (Coleman 2007; Conde-Green 2013; Sierra-Sánchez 2020)

step-by-step

Step-by-Step Procedure Guide

Complete Kit

Every Component.
One System.

Hover over each component to learn what it does

Harvesting Cannula
Harvesting Cannula
250 mm × 3 mm Ø
Vacuum Locking Syringes
Vacuum Locking Syringes
20 mL — automatic 300 mmHg negative
Fat Dialysing Station
Fat Dialysing Station
Closed-loop, up to 200 mL/cycle
Injection Cannulas x2
Injection Cannulas x2
Blunt tips — 150 mm × 2.1 mm Ø
Subcision Needle
Subcision Needle
16G — 150 mm ultra-sharp
01 — Harvesting

Harvesting Cannula & Vacuum Locking Syringe

250 mm × 3 mm Ø — 20 mL Syringe

Dedicated harvesting cannula paired with an automatic vacuum locking syringe that maintains negative pressure around 300 mmHg for controlled and fast fat harvesting.

Harvesting Cannula Vacuum Locking Syringe
Designed to be fast
12 port trilateral holes for consistent collection
Precise in fat sizing
Designed to harvest fat lobules <3 mm at ≤300 mmHg, to optimize graft survival and volume retention.
Gentle with donor site
Blunt tip design minimises trauma to surrounding tissue
Vacuum locking syringe
Automatic vacuum-locking system for easy, fast, and controlled harvesting.
02 — Purification

Fat Dialysing Station

At the core of the EXAFAT kit — an advanced lipoaspirate purification system designed to ensure safe, efficient, consistent, and respectful fat purification through a brief, active, and gentle continuous washing-filtration process. Operates in a closed-loop system.

SAFE
EFFICIENT
RESPECTFUL
REPEATABLE
Purification Station

Fat-Friendly

Findings from an internal comparative study on biological characterization of adipose tissue processed with EXAFAT vs. the Coleman technique and other commercially available kits.

MSCs VIABILITY*
COMPARISON STUDY
CELL VIABILITY AFTER SAMPLING:
Number of MSCs per mL of adipose tissue
IN VITRO PROLIFERATION*
COMPARISON STUDY
IN VITRO PROLIFERATION:
Increase factor (ratio between final and initial number of MSCs at 7/14/21 days)
EXAFAT
Macrofat competitor 1
Microfat competitor 1
Nanofat competitor 1
Nanofat competitor 2
Coleman Technique
FAT PURITY*
EXAFAT
EXAFAT sample 1
1
EXAFAT sample 2
2
COLEMAN
Coleman sample 3
3
Coleman sample 4
4

The EXAFAT samples (Fig. 1 & 2) exhibit a uniform composition, free from oil and red blood cells (RBCs).
In contrast, the images of the lipoaspirate obtained using the Coleman technique (Fig. 3 & 4) show blurred sections, indicating RBCs.

*Internal data provided by the Manufacturer

03 — Injection

Two Cannulas. Every Tissue Type.

Two blunt-tip cannulas with different tips: round tip for regular tissue and spatulated tip for scar tissue. Both cannulas share 2.1mm diameter to reduce the fat shear stress, a 150mm length for consistent 1mL ribbon delivery, and are bendable to optimize the injection precision and contour.

Round-tip Injection Cannula Spatulated-tip Injection Cannula
Subcision Needle
04 — Tissue Expansion

Subcision Needle

Ultra-sharp tip — 150 mm × 16 G

16G ultra-sharp needle with stylet for precise subcision (scar release/fasciotomy) and infusion or biopsy/drainage, enabling controlled tissue expansion after fat injection.

Documentation & Media

Everything You Need to Know

Download the product brochure, quick reference guide, or watch the full step-by-step procedure video.

Product Brochure
PDF · Download
Procedure Video
MP4 · Full Guide
Quick Reference Guide
PDF · Quick Guide
Partner with ABC

Become a Partner

Join the ABC network and bring EXAFAT to your market. Clinical training, marketing support, and dedicated account management included.

Apply to Partner →
Explore the ExaShape Line

ExaShape Biomaterial Membranes

Discover the full ExaShape line — pericardium-derived bilayer membranes for breast reconstruction.

Explore ExaShape

EXAFAT is a registered trademark of Advanced Biomedical Concept Srl · *Internal data provided by the Manufacturer

Questions

Frequently asked questions

What is EXAFAT®?

EXAFAT® is a complete sterile fat grafting system designed specifically for breast surgery, featuring a closed-loop fat dialysis technology with 50-micron microfiltration to maximise mesenchymal stem cell (MSC) viability and fat purity.

What is fat dialysis and why does it matter?

Fat dialysis filters harvested adipose tissue through a 50-micron membrane, removing blood, oils and tumescent fluid while preserving adipose-derived stem cells (MSCs). Clinical data shows this outperforms centrifugation and decantation in graft retention and viability.

What procedures is EXAFAT® designed for?

EXAFAT® is indicated for breast reconstruction, breast augmentation, breast explantation support, and breast reshaping procedures, providing surgeons with a single sterile all-in-one kit.

Is EXAFAT® CE-marked?

Yes. EXAFAT® is a CE-marked medical device under EU MDR 2017/745, manufactured in Italy.

How does EXAFAT® compare to centrifugation for fat grafting?

Independent studies show that EXAFAT® dialysis technology preserves a higher percentage of viable MSCs compared to standard centrifugation (1200g) and decantation techniques, leading to improved graft retention and patient outcomes.

What is included in the EXAFAT® kit?

The EXAFAT® system is a complete, sterile, ready-to-use kit that includes harvesting cannulas, a vacuum syringe, the 50-micron dialysing station, and injection cannulas — everything needed for a closed-loop fat grafting procedure in breast surgery.

Is EXAFAT® suitable for breast augmentation with fat?

Yes. EXAFAT® is designed for all fat-based breast procedures: reconstruction after mastectomy, cosmetic augmentation, volume correction after explantation, and reshaping. The closed-loop dialysis system makes it adaptable to different volumes and techniques.