Bovine Pericardium Biological Matrix · Your Bilayer Solution
Exashape
ExaShape is a product line obtained processing the pericardium of cattle. The membrane is gently processed with a "multiphasic" process that ensures pathogen inactivation while maintaining the three-dimensional structure of the collagen and its biomechanical properties.
Biological Matrix for Breast Reconstruction
ExaShape is a product line obtained processing the pericardium of cattle. The membrane is gently processed with a "multiphasic" process that ensures pathogen inactivation maintaining the three-dimensional structure of the collagen and its biomechanical properties.
Moreover, thanks to strict quality controls and standards throughout all pericardial tissue manufacturing process, the company aims to deliver reliable and effective medical devices that meet the needs of healthcare professionals and patients alike.
Bi-Layer
by Nature
Exashape preserves the original bi-layer structure of the bovine pericardium for optimal tissue regeneration and healing.
What is a biological matrix for breast reconstruction? →
Compact Layer
Protects the implant from external factors, reduces friction thanks to its smooth surface and provides structural support.
Porous Layer
Allows an early start of the integration process with progressive neovascularization, fibroblast colonization and collagen formation. Its porous structure supports tissue adherence and implant stability.
How it works
Mode of Action
1. Early Inflammation
Initiated immediately after implantation and dominated by M2 macrophages, associated with tissue repair. Growth factors are released to activate fibroblasts. Due to the low biological mass of Exashape, this inflammatory response is minimal, reducing the risk of seroma and oedema.
2. Neoangiogenesis
New blood vessels grow inside the porous layer of Exashape and progressively into the compact layer, promoting rapid fibroblast repopulation. Thanks to the permeability of the porous layer, this process begins earlier, reducing the risk of necrosis.
3. Collagen Formation
Fibroblasts produce patient-specific collagen, initially filling the porous layer and then the compact layer. Exashape becomes firmly integrated with the surrounding tissue, turning flexible and biologically active as native collagen is laid down.
4. Remodelling
Enzymatic degradation of the original matrix by collagenases creates new spaces, which are progressively replaced by organised collagen and new blood vessels. The resulting regenerated tissue is elastic, biologically active, and significantly thicker than the original membrane.
Our Product Line
Prepectoral
BioShield Pocket
Bovine pericardium meshed membrane with a patented pocket design for prepectoral breast reconstruction, to cover the anterior part of implants up to 560 cc in a quick, easy and safe way, without the need to suture it into the muscle.
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Prepectoral
BioShield Pocket 3D
3D pre-shaped bovine pericardium meshed membrane for prepectoral breast reconstruction, to cover the anterior part of implants up to 650 cc in a full non-touch, easier and quicker way, without the need to suture it into the muscle.
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Advanced
BioShield Pocket PRo
Enhanced bilayer pericardial pocket for complex breast reconstruction procedures requiring superior mechanical performance.
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Prepectoral
PREPEC
Bovine pericardium perforated membrane for breast reconstruction, designed to cover different parts of the implant according to the surgeon's needs.
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Subpectoral
Grid
Bovine pericardium perforated membrane in a half-moon shape designed for subpectoral breast reconstruction, to cover the lower part of the implant.
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Two Stages
Expander
Bovine pericardium rectangular perforated membrane designed for tissue expander use, supporting the expansion phase in two-stage breast reconstruction.
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NAC Reconstruction
NAC
Bovine pericardium perforated membrane designed for the support of nipple-areola complex reconstructions.
View product →Scientific References
- 1Pusic AL et al. Patient-reported outcomes 1 year after immediate implant-based breast reconstruction. J Clin Oncol. 2013.
- 2Wainwright DJ. Use of an acellular allograft dermal matrix (AlloDerm) in the management of full-thickness burns. Burns. 1995.
- 3Breuing KH, Warren SM. Immediate bilateral breast reconstruction with implants and inferolateral AlloDerm slings. Ann Plast Surg. 2005.
- 4Jansen LA et al. Acellular dermal matrix and the risk of complications with tissue expander and implant-based breast reconstruction. Ann Plast Surg. 2011.
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