ExaShape is obtained by processing the pericardium of cattle — a naturally strong, collagen-rich tissue. A gentle “multiphasic” process ensures pathogen inactivation while preserving the three-dimensional structure of the collagen and its biomechanical properties.
The result is a biological scaffold the body recognises and integrates — supporting revascularisation and host tissue regeneration, rather than a foreign body the immune system fights against.
ExaShape preserves the original bi-layer structure of the bovine pericardium for optimal tissue regeneration and healing.
Protects the implant from external factors, prevents friction thanks to its smooth surface, and provides structural support.
A highly porous structure that facilitates cell infiltration. It supports cytokines and growth factors, crucial for immediate tissue revitalization and the early formation of new blood vessels.
Dominated by M2 macrophages associated with tissue repair. Growth factors activate fibroblasts. Thanks to Exashape’s low biological mass, this response is minimal — reducing the risk of seroma and oedema.
New blood vessels grow inside the porous layer and progressively into the compact layer, promoting rapid fibroblast repopulation. Its permeability lets this begin earlier, reducing the risk of necrosis.
Fibroblasts produce patient-specific collagen, filling first the porous then the compact layer. Exashape becomes firmly integrated, turning flexible and biologically active.
Enzymatic degradation creates new spaces, progressively replaced by organised collagen and new vessels. The regenerated tissue is elastic, biologically active and significantly thicker than the original membrane.
Brief · Active · Gentle · Continuous
Fat dialysis is a brief, active purification process that continuously and gently removes tumescent fluid, blood, oil and excess fluid from harvested fat.
EXAFAT employs a 50-micron microfiltration technology: liquid waste passes through under controlled hydrostatic pressure while the purified fat — including the SVF niche — is retained. The result is a significant reduction of toxic and inflammatory triggers while maintaining the structural integrity and biological viability of the adipose tissue.
more purified fat on average than the same input processed by decantation.
more purified fat on average than Coleman centrifugation.
clean residual fluid retained (±5%) vs 33% non-purified with decantation.
Maintaining a degree of hydration helps protect adipocytes and stromal cells from mechanical damage during injection and promotes a more uniform fat distribution; excessive dehydration has been associated with increased shear stress and reduced adipocyte viability (Coleman 2007; Conde-Green 2013; Sierra-Sánchez 2020).
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A bovine pericardium biological matrix is a decellularised, collagen-rich scaffold. Once implanted, it supports host-cell repopulation and revascularisation, so the patient's own tissue gradually integrates with and remodels the matrix rather than encapsulating a permanent synthetic material.
A lower, well-controlled inflammatory response is associated with better integration and fewer matrix-related complications. Acellular bovine pericardium is designed to present a low-immunogenicity collagen scaffold, in contrast to the higher chronic-inflammation profile that can accompany some synthetic materials.
Over roughly 3–12 months the scaffold is progressively repopulated by host cells and vascularised, becoming incorporated into the patient's own soft tissue. Unlike permanent synthetic mesh, a biological matrix is remodelled rather than remaining indefinitely as a foreign body.
Yes. The tissue undergoes a controlled decellularisation process that removes cellular material while preserving the native collagen architecture, producing an acellular biological scaffold suitable for implantation.
From the ExaShape® biological matrix for breast reconstruction to the EXAFAT® fat-grafting system — explore the full range of ABC devices.
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